The MR-Research Centre at Aarhus University Hospital provides facilities for advanced bioimaging. With a transdisciplinary approach the latest advances in natural sciences and engineering are translated to biomedicine and subsequently implemented in clinical applications.
The Centre is hosting a high number of pre-clinical and clinical research programs. The top scientific competences are found in oncology, kidney physiology, brain- and cardiovascular functionality, orthopedics and stem cell culturing and application. The affiliated researchers have an educational background as doctors, physicists, chemists, engineers, molecular biologists and psychologists.
Interventional systems for advanced bio-imaging are based on the hyperpolarization-MR using a number of bio-probes for in vivo quantification of metabolic fluxes.
The Centre has 3T and 1.5 T clinical scanners from various vendors. Two of these are together with a high-field (9.4T) horizontal small bore magnet allocated for research every day.
The MR-Centre has established the new MR-hyperpolarization technology. This makes Denmark the third country in Europe to gain access to very detailed information on metabolic processes. The technique is just now adjusted pre-clinically before being offered to patients. The Centre aims for even better decisions of treatments in cancer patients, understanding of tissue changes following stroke in the heart muscle or in the brain and metabolic diseases like diabetes.
The figure to the left shows the intensity of a specific metabolic reaction in the kidneys. To the right is shown metabolic reactions in a tumour. The presence of lactate indicates that part of the tumour is perishing.
A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal has generously donated 17.5 million dkk to the MR Center.
The donation will be used for further development of the MR-hyperpolarization technology.
The Danish Strategic Research Council has granted a group of researchers 17.5 million DKK.
LIFE-DNP: hyperpolarized magnetic resonance for in vivo quantification of lipid, sugar and amino acid metabolism in lifestyle related diseases.