THE MR RESEARCH CENTRE AT AARHUS UNIVERSITY HOSPITAL

The MR-Research Centre at Aarhus University Hospital provides facilities for advanced bioimaging. With a transdisciplinary approach the latest advances in natural sciences and engineering are translated to biomedicine and subsequently implemented in clinical applications.

The Centre is hosting a high number of pre-clinical and clinical research programs. The top scientific competences are found in oncology, kidney physiology, brain- and cardiovascular functionality, orthopedics and stem cell culturing and application. The affiliated researchers have an educational background as doctors, physicists, chemists, engineers, molecular biologists and psychologists.

Interventional systems for advanced bio-imaging  are based on the hyperpolarization-MR using a number of bio-probes  for in vivo quantification of metabolic fluxes.

The Centre has 3T and 1.5 T clinical scanners from various vendors. Two of these  are together with a high-field (9.4T) horizontal small bore magnet allocated for research every day. 


   

LATEST NEWS

Ph.d. defense by Esben Søvsø Szocska Hansen

Esben Søvsø Szocska Hansen will defense his Ph.d. thesis on Monday October 2nd, 14:00

under the title "Magnetic Resonance Imaging of Cardiac Metabolism and Kidney Function"

Read more

New Publications

Lottes audioslides from ISMRM 2017
https://www.youtube.com/watch?v=Wn6UnKhgbCk

Diabetes induced renal urea transport alterations assessed with 3D hyperpolarized 13C,15N-Urea,by Lotte B. Bertelsen, Per M. Nielsen, Haiyun Qi, Thomas S. Nørlinger, Xiaolu Zhang, Hans Stødkilde-Jørgensen and Christoffer Laustsen

Q&A with Lotte Bertelsen and Christoffer Lausten from ISMRM 2017
www.ismrm.org/qa-with-lotte-bertelsen-and-christoffer-lausten/

 

 

MR-hyperpolarisation

The MR-Centre has established the new MR-hyperpolarisation technology. This makes Denmark the third country in Europe to gain access to very detailed information on metabolic processes. The technique is just now adjusted pre-clinically before being offered to patients. The Centre aims for even better decisions of treatments in cancer patients, understanding of tissue changes following stroke in the heart muscle or in the brain and metabolic diseases like diabetes.

The figure to the left shows the intensity of a specific metabolic reaction in the kidneys. To the right is shown metabolic reactions in a tumour. The presence of lactate indicates that part of the tumour is perishing.

  

Latest major grants

  • Karen Elise Jensens Fond has donated 5.9 million ddk to the MR centret. 
  • A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal has generously donated 17.5 million dkk to the MR Center.  

    The donation will be used for further development of the MR-hyperpolarization technology.
 

LIFE-DNP

The Danish Strategic Research Council has granted a group of researchers 17.5 million DKK.

LIFE-DNP: hyperpolarized magnetic resonance for in vivo quantification of lipid, sugar and amino acid metabolism in lifestyle related diseases.