This course aims to provide participants with a thorough introduction to both spectroscopy and imaging techniques using proton and non-proton (x-nuclear) nuclei. It combines theoretical lectures with practical hands-on training to cover the full spectrum of MR methodology - from fundamental principles to advanced applications.
 

The course is divided into two complementary parts:

Theoretical Lectures
Participants will be introduced to key concepts and advanced methods, including:

• Proton MR spectroscopy (¹H-MRS) and spectroscopic imaging (MRSI)
• Hardware considerations for x-nuclear MR (coils, transmit/receive chains)
• Pulse sequence design and optimization
• Reconstruction and quantification of spectroscopic and imaging data
• Relevant biological and biochemical background
• Clinical and research applications across various nuclei

Special emphasis will be placed on thermally-polarized non-proton nuclei such as ²H (deuterium), ²³Na (sodium), and ³¹P (phosphorus), highlighting their specific signal characteristics and potential for metabolic and functional imaging.

Practical Hands-On Training
Through dedicated sessions on GE Healthcare MRI systems, participants will:

• Learn to set up and run MRS and x-nuclear MR sequences
• Acquire and process real datasets
• Practice basic quantification and interpretation workflows
• Gain experience with system-specific tools and challenges

By the end of the course, attendees will have developed both the theoretical understanding and practical skills needed to carry out and evaluate MR spectroscopy and x-nuclear imaging studies.