THE MR RESEARCH CENTER AT AARHUS UNIVERSITY

 

The Magnetic Resonance (MR) Research Center, Department of Clinical Medicine, Aarhus University, located at Aarhus University Hospital, provides state-of-the-art facilities and resources for advanced bioimaging research. 

Our core mission is to develop and translate new MR technology to researchers and clinicians to push the boundaries for excellence in magnetic resonance spectroscopy and imaging.

   


Life-DNP

The Danish Strategic Research Council has granted a group of researchers 17.5 million DKK.

LIFE-DNP: hyperpolarized magnetic resonance for in vivo quantification of lipid, sugar and amino acid metabolism in lifestyle related diseases.

Hyperpolarization

What is hyperpolarization?

Hyperpolarization is defined as a method to increase the signal that is obtainable with magnetic resonance spectroscopy or imaging beyond what is possible at thermal equilibrium or in other words under normal conditions.

The hyperpolarization method, dissolution dynamic nuclear polarization (d-DNP) is able to increase the signal more than 20.000 times.

What is it good for?

The signal amplification allows us to trace the individual cells of the body’s uptake and breakdown of specific metabolic substrates in real time. This provides improved specificity for a great deal of physiological and pathophysiological conditions, by tracing the enzymatic conversion of important intermediates in lipid, sugar and amino acid metabolism.