Publications

2025-2026

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Mózes FE, Clarke WT, Tyler A, Karkouri J, Niess F, Miller JJJJ et al. Repeatability of Rapid Human Cardiac Phosphorus MRSI (31P-MRSI) Using Concentric Ring Trajectory Readouts at 7 T. Magnetic Resonance in Medicine. 2026 May;95(5):2508-2514. Epub 2025. doi: 10.1002/mrm.70220
Rooney CHE, Lau JYC, Hansen ESS, Christensen NV, Dang DA, Petersson K et al. Stable electron-irradiated [1-13C]alanine radicals for metabolic imaging with dynamic nuclear polarization. Science Advances. 2025 Nov 21;11(47):1-16. eadz4334. doi: 10.1126/sciadv.adz4334
Carter RD, Purnama U, Castro-Guarda M, Montes-Aparicio CN, Chandran A, Mbasu R et al. Systems Biology and Functional Assessments of Human iPSC-Cardiomyocyte Models of Insulin Resistance Capture Key Hallmarks of Diabetic Cardiomyopathy. Diabetes. 2025 Nov 1;74(11):1929-1945. Epub 2025 Sept 16. doi: 10.2337/db25-0204
Zattoni M, Bontempi L, Ringgaard S, Luraghi G, Benhassen LL, Johansen P et al. In silico modelling of aortic annuloplasty: hemodynamic assessment through in vitro experiments and in vivo MRI. Computer Methods and Programs in Biomedicine. 2026 Apr;277:109246. doi: 10.1016/j.cmpb.2026.109246
Abrahams G, Štuhec A, Spreng V, Henry R, Kempf I, James J et al. Quantum spin resonance in engineered proteins for multimodal sensing. Nature. 2026 Jan 29;649(8099):1172-1179. doi: 10.1038/s41586-025-09971-3
Anderson S, Karlstaedt A, Young M, Karatzia L, Cullen F, Chen J et al. Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy. Nature Cardiovascular Research. 2026 Feb;5(2):138-154. doi: 10.1038/s44161-025-00769-0
Khan AS, Laustsen C. Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI. Journal of Magnetic Resonance Imaging. 2026 Feb;63(2):310-327. Epub 2025 Sept 1. doi: 10.1002/jmri.70084

2024

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Ye Z, Song B, Laustsen C. Hyperpolarized 13C MRI in hepatocellular carcinoma: Unmet questions during clinical translation. Chinese Medical Journal. 2024 Jul 5;137(13):1516-1518. doi: 10.1097/CM9.0000000000003120
Zhao Y, Lerche MH, Karlsson M, Olin RB, Søvsø Szocska Hansen E, Aastrup M et al. Hyperpolarized Water for Coronary Artery Angiography and Whole-Heart Myocardial Perfusion Quantification. Tomography - A Journal for Imaging Research. 2024 Jul;10(7):1113-1122. doi: 10.3390/tomography10070084, 10.3390/tomography10070084
Meskin M, Starkey PA, Kaspersen AE, Ringgaard S, Sand SG, Nygaard JV et al. Investigating the importance of left atrial compliance on fluid dynamics in a novel mock circulatory loop. Scientific Reports. 2024 Jan 22;14(1):1864. 1864. doi: 10.1038/s41598-024-52327-6
Krogh E, Ringgaard S, Kelly B, Rungsiprakarn P, Rychik J, Gaynor JW et al. Lung volumes are increased in fetuses with transposition of the great arteries on intrauterine MRI. Cardiology in the Young. 2024 Dec 1;34(12):2650-2655. doi: 10.1017/S1047951124026398
Kelly B, Thorup L, Telinius N, Mohanakumar S, Ringgaard S, Poulsen SH et al. Lymphatic morphology and function in chronic right heart failure due to secondary tricuspid valve regurgitation. International Journal of Cardiology. 2024 Oct 15;413:132399. doi: 10.1016/j.ijcard.2024.132399
Hamelink TH, Orgurlu B, Pamplona CC, Castelein J, Bennedsgaard S, QI H et al. Magnetic resonance imaging as a non-invasive adjunct to conventional assessment of functional differences between kidneys in vivo and during ex vivo normothermic machine perfusion. American Journal of Transplantation. 2024 Oct;24(10).
Hamelink TL, Ogurlu B, Pamplona CC, Castelein J, Bennedsgaard SS, Qi H et al. Magnetic resonance imaging as a noninvasive adjunct to conventional assessment of functional differences between kidneys in vivo and during ex vivo normothermic machine perfusion. American Journal of Transplantation. 2024 Oct;24(10):1761-1771. doi: 10.1016/j.ajt.2024.04.001
Chaumeil MM, Bankson JA, Brindle KM, Epstein S, Gallagher FA, Grashei M et al. New Horizons in Hyperpolarized 13C MRI. Molecular Imaging and Biology. 2024 Apr;26(2):222-232. Epub 2023 Dec 26. doi: 10.1007/s11307-023-01888-5
Xu J, Vaeggemose M, Schulte RF, Yang B, Lee CY, Laustsen C et al. PyAMARES, an Open-Source Python Library for Fitting Magnetic Resonance Spectroscopy Data. Diagnostics. 2024 Dec;14(23):2668. doi: 10.3390/diagnostics14232668
Bøgh N, Vaeggemose M, Schulte RF, Hansen ESS, Laustsen C. Repeatability of deuterium metabolic imaging of healthy volunteers at 3 T. European Radiology Experimental. 2024 Mar;8(1):44. doi: 10.1186/s41747-024-00426-4
Axelsen JS, Andersen S, Ringgaard S, Smal R, Lluciá-Valldeperas A, Nielsen-Kudsk JE et al. Right ventricular diastolic adaptation to pressure overload in different rat strains. Physiological Reports. 2024 Jul;12(13):e16132. doi: 10.14814/phy2.16132
Bisgaard M, Houlind KC, Blankholm AD, Ringgaard S, Christensen J, Precht H. Validation of MRI assessment of foot perfusion for improving treatment of patients with peripheral artery disease. Radiography. 2024 Jul;30(4):1116-1124. doi: 10.1016/j.radi.2024.05.007

2023

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Burrage MK, Lewis AJ, Miller JJJ. Functional and Metabolic Imaging in Heart Failure with Preserved Ejection Fraction: Promises, Challenges, and Clinical Utility. Cardiovascular Drugs and Therapy. 2023 Apr;37(2):379-399. doi: 10.1007/s10557-022-07355-7
Hu JY, Vaziri S, Bøgh N, Kim Y, Autry AW, Bok RA et al. Investigating cerebral perfusion with high resolution hyperpolarized [1-13C]pyruvate MRI. Magnetic Resonance in Medicine. 2023 Dec;90(6):2233-2241. doi: 10.1002/mrm.29844
Schutter R, van Varsseveld OC, Lantinga VA, Pool MBF, Hamelink TH, Potze JH et al. Magnetic resonance imaging during warm ex vivo kidney perfusion. Artificial organs. 2023 Jan;47(1):105-116. doi: 10.1111/aor.14391
Agergaard J, Yamin Ali Khan B, Engell-Sørensen T, Schiøttz-Christensen B, Jørgen Østergaard L, Hejbøl EK et al. Myopathy as a cause of Long COVID fatigue: Evidence from quantitative and single fiber EMG and muscle histopathology. Clinical Neurophysiology. 2023 Apr;148:65-75. doi: 10.1016/j.clinph.2023.01.010
Ellis CM, Yuan D, Mózes FE, Miller JJ, Davis JJ. Reversible pH-responsive MRI contrast with paramagnetic polymer micelles. Chemical Communications. 2023 Jan;59(12):1605-1608. doi: 10.1039/d2cc06255k
Madsen S, Bak SY, Yde CC, Jensen HM, Knudsen TA, Bæch-Laursen C et al. Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet. Metabolites. 2023 Aug;13(9):974. doi: 10.3390/metabo13090974

2022

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Ye Z, Song B, Lee PM, Ohliger MA, Laustsen C. Hyperpolarized carbon 13 MRI in liver diseases: recent advances and future opportunities. Liver International. 2022 May;42(5):973-983. Epub 2022 Mar 1. doi: 10.1111/liv.15222
Jørgensen SH, Bøgh N, Hansen E, Væggemose M, Wiggers H, Laustsen C. Hyperpolarized MRI - An update and future perspectives. Seminars in Nuclear Medicine. 2022 May;52(3):374-381. Epub 2021 Nov 13. doi: 10.1053/j.semnuclmed.2021.09.001
Staehr C, Rohde PD, Krarup NT, Ringgaard S, Laustsen C, Johnsen J et al. Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function. Journal of the American Heart Association. 2022 Apr;11(7):e021814. Epub 2022 Mar 15. doi: 10.1161/JAHA.121.021814
Sanchez-Heredia JD, Olin RB, Grist JT, Wang W, Bøgh N, Zhurbenko V et al. RF coil design for accurate parallel imaging on 13C MRSI using 23Na sensitivity profiles. Magnetic Resonance in Medicine. 2022 Sept;88(3):1391-1405. doi: 10.1002/mrm.29259
Laustsen C, Bøgh N. Sodium MRI of the Renal Corticomedullary Gradient. Radiology. 2022 May;303(2):390-391. 213007. Epub 2022 Feb 8. doi: 10.1148/radiol.213007
Dearlove DJ, Soto Mota A, Hauton D, Pinnick K, Evans RD, Miller J et al. The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation. Physiological Reports. 2022 May;10(10):e15309. doi: 10.14814/phy2.15309
Bech SK, Qi H, Mariager CØ, Hansen ESS, Ilicak E, Zöllner FG et al. The number of glomeruli and pyruvate metabolism is not strongly coupled in the healthy rat kidney. Magnetic Resonance in Medicine. 2022 Feb;87(2):896-903. doi: 10.1002/mrm.29025
Louise M Binderup M, Smerdel M, Borgwadt L, Beck Nielsen SS, Madsen MG, Møller HU et al. von Hippel-Lindau disease: Updated guideline for diagnosis and surveillance. European Journal of Medical Genetics. 2022 Aug;65(8):104538. doi: 10.1016/j.ejmg.2022.104538

2021

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2020

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Nielsen PM, Mariager CØ, Mølmer M, Sparding N, Genovese F, Karsdal MA et al. Hyperpolarized [1-13C] alanine production: A novel imaging biomarker of renal fibrosis. Magnetic Resonance in Medicine. 2020 Oct;84(4):2063-2073. Epub 2020 May 25. doi: 10.1002/mrm.28326
Pedersen MV, Andelius TCK, Brogård Andersen H, Andersen M, Hansen LH, Bøgh N et al.. Hypothermia and neonatal heart rate variability – a study in healthy piglets. 2020. Poster session presented at 8th Congress of the European Academy of Paediatric Societies.
Sánchez-Heredia JD, Olin RB, McLean MA, Laustsen C, Hansen AE, Hanson LG et al. Multi-site benchmarking of clinical 13C RF coils at 3T. Journal of Magnetic Resonance. 2020;318:106798. doi: 10.1016/j.jmr.2020.106798
Bøgh N, Agger P, Christensen CO, Skov MN, Laustsen C, Wang T et al. New Device for Noninvasive Telemetric Monitoring of Vital Signs in Healthy and Newly Operated Piglets. Journal of the American Association for Laboratory Animal Science. 2020 Jan;59(1):90-93. Epub 2019 Dec 5. doi: 10.30802/AALAS-JAALAS-19-000052
Dollerup OL, Chubanava S, Agerholm M, Søndergård SD, Altıntaş A, Møller AB et al. Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men. The Journal of Physiology. 2020 Feb;598(4):731-754. Epub 2019 Nov 11. doi: 10.1113/JP278752
Nielsen PM, Mariager CØ, Rasmussen DGK, Mølmer M, Genovese F, Karsdal MA et al. Noninvasive Assessment of Fibrosis Following Ischemia/Reperfusion Injury in Rodents Utilizing Na Magnetic Resonance Imaging. Pharmaceutics. 2020 Aug;12(8):1-15. 775. doi: 10.3390/pharmaceutics12080775
van Erp AC, Qi H, Jespersen NR, Hjortbak MV, Ottens PJ, Wiersema-Buist J et al. Organ-specific metabolic profiles of the liver and kidney during brain death and afterwards during normothermic machine perfusion of the kidney. American Journal of Transplantation. 2020 Sept 1;20(9):2425-2436. Epub 2020 Apr 13. doi: 10.1111/ajt.15885
Villa G, Ringgaard S, Hermann I, Noble R, Brambilla P, Khatir DS et al. Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper. Magnetic Resonance Materials in Physics, Biology and Medicine. 2020;33(1):3-21. Epub 2019 Aug 17. doi: 10.1007/s10334-019-00772-0
Stødkilde-Jørgensen H, Laustsen C, Hansen ESS, Schulte R, Ardenkjaer-Larsen JH, Comment A et al. Pilot Study Experiences With Hyperpolarized [1-13C]pyruvate MRI in Pancreatic Cancer Patients. Journal of Magnetic Resonance Imaging. 2020 Mar 1;51(3):961-963. Epub 2019 Aug 1. doi: 10.1002/jmri.26888
Hockings P, Laustsen C, Joles JA, Mark PB, Sourbron S. Special issue on magnetic resonance imaging biomarkers of renal disease. Magnetic Resonance Materials in Physics, Biology and Medicine. 2020 Feb;33(1):1-2. doi: 10.1007/s10334-019-00822-7
Mendichovszky I, Pullens P, Dekkers I, Nery F, Bane O, Pohlmann A et al. Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA. Magnetic Resonance Materials in Physics, Biology and Medicine. 2020 Feb;33(1):131-140. Epub 2019 Oct 18. doi: 10.1007/s10334-019-00784-w

2019 and earlier publications

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Mariager CØ, Lindhardt J, Nielsen PM, Schulte RF, Ringgaard S, Laustsen C. Fractional Perfusion: A Simple Semi-Parametric Measure for Hyperpolarized C-13 MR. IEEE Transactions on Radiation and Plasma Medical Sciences. 2019;3(4):523-527. doi: 10.1109/TRPMS.2019.2905724
Laustsen C, Lipsø K, Østergaard JA, Nielsen PM, Bertelsen LB, Flyvbjerg A et al. High Intrarenal Lactate Production Inhibits the Renal Pseudohypoxic Response to Acutely Induced Hypoxia in Diabetes. Tomography - A Journal for Imaging Research. 2019 Jun;5(2):239-247. doi: 10.18383/j.tom.2019.00003
Kurhanewicz J, Vigneron DB, Ardenkjaer-Larsen JH, Bankson JA, Brindle K, Cunningham CH et al. Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology: Path to Clinical Translation in Oncology. NeoPlasia. 2019 Jan 1;21(1):1-16. doi: 10.1016/j.neo.2018.09.006
Sanchez-Heredia JD, Johansen DH, Hansen RB, Szocska Hansen ES, Laustsen C, Zhurbenko V et al. Improved Decoupling for Low Frequency MRI Arrays using Non-conventional Preamplifier Impedance. IEEE transactions on bio-medical engineering. 2019 Jul;66(7):1940-1948. 8533360. Epub 2018 Nov 13. doi: 10.1109/TBME.2018.2881203
Dalgaard LB, Dalgas U, Andersen JL, Rossen NB, Møller AB, Stødkilde-Jørgensen H et al. Influence of Oral Contraceptive Use on Adaptations to Resistance Training. Frontiers in Physiology. 2019 Jul;10:1-14. 824. doi: 10.3389/fphys.2019.00824